Focal Segmental Glomerulosclerosis and Complement Genetic Study Report


Focal Segmental Glucerulosclerosis and Complement Genetic Study

Focal segmental glomerulosclerosis consists of a sclerosis process affecting the renal glomeruli. The underlying genetic mutations compromise the functionality of the podocytes, responsible for the synthesis of many components of the glomerular basement membrane. The complement system, part of innate immunity, may contribute to tubular injury.

more than 30 genes analyzed

It is recommended if:

Hemolytic Uremic Syndrome and Autosomal Dominant Interstitial Nephritis are two medical conditions affecting the excretory system. The first has an infectious origin but there are atypical, rarer forms whose onset is genetic in nature. The second involves, however, a picture of progressive renal failure, tubulointerstitial nephropathy and bland urinary sediment, in absence of glomerular lesions. Its etiology is exclusively genetic.

List of main conditions:

  • Glomerulosclerosis, focal segmental, 1
  • Nephrotic syndrome, type 3
  • Nephrotic syndrome, type 9
  • Available in less than 24 hours
  • Based on Whole Genome Sequencing
  • Investigates SNP and Indel mutations up to 150 bp


How will my data be used?

Your data is yours. Which is why we have developed proprietary software linked to a dedicated platform, the Genome Manager, to provide you with unique access to your data whenever you want, wherever you are.

How can my doctor use the results?

You will be provided with a digital version of the raw data and reports. Thanks to these in-depth tools, you will be able to share your preferred information with your geneticist and/or doctor to indicate and plan the healthiest course for you. 

How will I receive my reports?

The first thing to do when you receive your kit is to register it on your Genome Manager account. Dante's proprietary platform will keep you up-to-date on all stages of your genetic journey, providing you with the real-time status of your sample and where you can download your free report and raw data* at any time.

*Raw data will be available free of charge for the first 30 days after release.

How can I add other reports to my account?

At any time, you can log into your Genome Manager account and visit the Shop section. Here you will find a catalog with more than 150 additional reports dedicated to all areas of health. In addition, by subscribing to our newsletter you can always see new reports and panel updates.

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