Introduction

World Food Day is a special occasion to reflect on the significance of food in our lives. But today, we want to delve into how genetic science can open new horizons in our understanding of food and nutrition. The Whole Genome Sequencing Analysis (WGS) and the Nutrigenetic Panel have emerged as powerful tools that offer personalized insights into our genetic predispositions related to nutrition. These insights can pave the way for tailored dietary plans that can enhance our overall well-being.

The Power of Whole Genome Sequencing Analysis

MyGenome Sequencing test is a cutting-edge genetic technology that decodes an individual's entire genetic makeup. It provides a comprehensive overview of your unique genetic code, including variants associated with various aspects of health and well-being. This information extends to your relationship with food, diet, and nutrition.

Unveiling Your Nutrigenetic Profile

Our genes play a significant role in how our bodies metabolize and respond to different nutrients, vitamins, and dietary components. The Nutrigenetic Panel, based on the MyGenome Sequencing Test, focuses on identifying specific genetic variations related to nutrition.

By analyzing your Nutrigenetic profile, you can gain insights into:

How you transform, use, store and eliminate (or metabolize) the fats you introduce to your diet has an enormous impact on your health and the risk of developing severe diseases. By modulating the quantity and quality of fats you eat based on this genetic test, you may be able to keep your cholesterol and triglyceride levels under control, improve your weight and optimize your response to dietary fats. You will also find the genetic variants influencing your need for more omega 3.

• Circadian Cycle and Metabolism

Several mechanisms regulate appetite and energy intake, including stress, sleep disturbances and dysregulated eating patterns (i.e., eating late at night and leaving long gaps between meals), which can negatively impact the quantity and quality of your food and the calories we introduce. Genetics can also influence your daily rhythms and appetite. In this section, you will find your Nutrigenetics test results regarding genes regulating energy intake and the physiological day-night cycles. 

Maintaining average glucose and insulin levels is necessary to avoid developing insulin resistance and eventually type 2 diabetes (T2D). A chronic elevation in either glycemic (sugar levels in your blood) or insulin can also increase your body inflammation, cause weight gain, and predispose you to chronic diseases such as those affecting the cardiovascular system and kidneys. In this section, you will find the results of your Nutrigenetics test regarding the most well studied and scientifically validated genetic variants that have been demonstrated to increase T2D risk and affect how you respond to sugars and carbohydrates. Therefore, if your results show that you carry variations in these genes, you may decrease your risk by improving the types and quantity of carbohydrates in your diet.

• Food Sensitivities

Our body may react in a negative or inappropriate way to certain substances contained in foods and beverages. These reactions are not proper allergies but a sort of sensitivity, which may or may not involve the immune system. In this section of your Nutrigenetics report, you will find the results regarding genetic variants that affect the way you metabolize caffeine, alcohol and lactose. These polymorphisms do not cause any propensity to allergic reactions but change the function of specific enzymes that metabolize these substances.

The importance of vitamins and minerals for the well-being of our organism is easily revealed by the serious consequences that can be encountered in the event of a deficiency. These nutrients, of which small quantities are sufficient, although they do not possess an "energy value", are indispensable in numerous physiological processes (such as vitamin A in vision or K in blood coagulation) and metabolic processes (especially vitamins of the group B). Furthermore, vitamins act as enzymatic and antioxidant cofactors, regulate the homeostasis of other elements (just think of the role of vitamin D in calcium metabolism) and allow correct fetal development, especially as regards the nervous system. Minerals are indispensable in the hydro-salt balance, enzymatic function, muscle contraction (calcium) and hormone synthesis (iodine), among other functions. In this section of your Nutrigenetics report, you will find the most well-studied and scientifically validated genetic variants that have been demonstrated to influence vitamin and minerals levels.

Liver detoxification occurs in two phases; in Phase I, toxins are transformed into intermediate metabolites, which can be even more reactive and potentially detrimental. The enzymes in this phase belong mainly to a family called CYP 450. In Phase II, these intermediates are “conjugated” (bound with) other molecules to make them more soluble and easier to be excreted. In this section, you will find the results of your Nutrigenetics test regarding the most well-studied and scientifically validated genetic variants in two essential CYP 450 encoding genes and two genes encoding for Phase II enzymes. If you carry one or more of these variants, you should aim to balance both Phases of liver detoxification.

Discover the Nutrigenetic Panel

Tailoring Your Diet to Your DNA

Armed with your Nutrigenetic profile from Whole Genome Sequencing Analysis, you can work with a registered dietitian or nutritionist to create a personalized dietary plan. This plan takes into account your genetic predispositions, allowing you to optimize your nutrition and overall health.

For example, if your genes indicate a higher risk of vitamin D deficiency, your dietitian may recommend increased sun exposure or specific dietary supplements. If you have a genetic tendency to process carbohydrates slowly, they may suggest a balanced carbohydrate intake and regular physical activity to manage blood sugar levels effectively.

Empowering Your Food Choices

The synergy of Whole Genome Sequencing Analysis and the Nutrigenetic Panel empowers you to make more informed food choices. It's a proactive approach to health that acknowledges the unique genetic factors that influence our relationship with food. By aligning your diet with your DNA, you can optimize your nutrition, reduce the risk of dietary-related health issues, and embark on a path to a healthier and more satisfying relationship with food.

This World Food Day, consider the transformative potential of genetic insights on your dietary choices. Embrace the power of Whole Genome Sequencing Analysis and the Nutrigenetic Panel to unlock a brighter, healthier future through personalized nutrition. Your genes hold the key to a more tailored and effective approach to food, ensuring you savor every bite with confidence.