Angela was a 4-year-old child when, suddenly, started to present seizures and, gradually, other associated neurological conditions. She visited many doctors and took multiple drugs. Unfortunately, with limited effects. Not knowing what to do about her daughter, Emma, Angela’s mother, decided to opt for Dante Labs “My Full DNA” Analysis. A saliva sample was taken and shipped out to Dante Labs, then the entire genome analysis was performed and. After 12 weeks, she received a report via email where a bunch of genetic variants were listed and scientifically explained. The report was about “Epilepsy and seizures associated with neurological conditions”, surveying 128 genes. Angela’s mother decided to go to a geneticist to get an opinion. He found the Dante Labs report very informative with comprehensive actionable information and ended up with a final diagnosis. Angela was affected by a specific form of epilepsy called GLUT-1 deficiency, where an insufficient level of glucose reaches the brain. The diagnosis was life-changing. Angela started a specific diet - ketogenic diet - and tailed down her anticonvulsant medicines. Today Angela is living a better life.
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Why did Johannes choose Dante Labs?
Johansen has a family history that gives him a good reason to be concerned about his health. Many of his close relatives have had various diseases like Motor Neurone Disease (MND), Myoadenylate deaminase (MAD) deficiency, Hereditary Hemochromatosis, Charcot-Marie-Tooth Disease (CMT, CMT4, CMT4A, CMT4 SB2, CMT1A) and inflammatory myopathy. There are also a few isolated cases of individuals on both sides of his family that have Duchenne, Beckers, and Thomsen. Also, since the high prevalence of Dystrophia Myotonica (DM1) in Iceland, most of his family members are affected by this disease.
After this troubling family history in term of diseases, Johannes decided to dig deeper into his genetic makeup and go to an NHS* Hospital (hereinafter, “the Hospital”: we prefer not to disclose the name of the British public hospital - ed.). Here is what Johannes directly reported: “The Hospital was supposed to have the most advanced Genetic Department in Scotland but, in reality, they are very far behind what Dante Labs produces and all their research is based on blood or muscle samples only. They can only look at a single gene at a time. They talk about how advanced they are but it is more related to voodoo practice than precise DNA science… Looking back at some of the diagnosis that has been done in the past to explain what was happening to my body and why some of my symptoms are the way they are, might not be 100% correct and should perhaps be looked at again”.
*National Health Service is the name used for each of the public health services in the United Kingdom
How Dante Labs ‘results have helped Johannsen
After having received the final results from Dante Labs, which provides a thorough and accurate report finding the real diseases afflicting him, Johannsen decided to go to two geneticists to get an opinion from two insiders. Here is what Johannsen said about this: “They were very impressed with the data that I had received from Dante Labs. Finally, I would like to thank Dante Labs for being so helpful and providing excellent molecular genetic data and the surprising find in my data is related to Noonan Syndrome – A2ML1 gene mutation and RUNX1 Deficiency – involving mutations in the RUNX1 gene that have been related to different types of Leukaemia and related blood disorders. This information has now been acted upon and blood samples have been taken and being analyzed… The data I have received from Dante Labs is like a Goldmine”.