Science held to the standard medicine already trusts.
Sequenced in an ISO 15189-accredited laboratory. Classified to ACMG standards. Published in Nature Communications. 99.98% accuracy across 100,000+ genomes at 30X clinical depth.
The institutional accreditations behind every result Dante produces.
The accreditation frameworks that separate a medical result from a consumer report.
The International Standard for Medical Laboratories
ISO 15189 is the accreditation that separates a medical laboratory from a testing service. It requires documented competence in every stage of the testing process — from sample receipt to result delivery. Dante's laboratories hold this accreditation as an operating standard.
The Gold Standard for Laboratory Quality
The College of American Pathologists accreditation is the most rigorous laboratory quality program in existence. CAP inspects Dante's labs through unannounced on-site inspections — reviewing every process from reagent handling to result interpretation. It is the standard hospitals use to approve laboratories for clinical use.
Clinical Laboratory Improvement Amendments
Clinical Laboratory Improvement Amendments (CLIA) certification is the federal standard that authorizes a laboratory to perform clinical testing on human specimens in the United States. Dante's results meet the standard required for clinical use in US medical decision-making — as clinical-grade findings a physician can act on.
The standard used by Mayo Clinic, Johns Hopkins, and NHS Genetics
Every variant identified through Dante's sequencing is classified according to guidelines from the American College of Medical Genetics and Genomics and the Association for Molecular Pathology (ACMG/AMP) — the international standard for clinical variant interpretation. The same framework used by Mayo Clinic, Johns Hopkins, NHS genetics, and major academic medical centers worldwide.
Dante's labs sequence every base pair in your genome — from sample to report, under one accredited operation.
Every base pair — the individual chemical units that make up your DNA. Read 30 times. Not just selected markers.
Dante maintains clinical-grade laboratories holding both ISO 15189 and CAP accreditation — the same dual standard required by hospital systems when approving laboratories for clinical use. This is not a software layer built on top of third-party sequencing. Dante's labs perform the sequencing, apply the classification, and produce the reports under one accredited operation.
At 30X coverage, every base pair in your genome is read 30 times independently, cross-referenced for consistency, and validated against the clinical accuracy standard required for physician-usable results: 99.98% across more than 100,000 genomes.
"The diagnosis was life-changing. Today my daughter is living a better life."
Validated by independent clinical institutions worldwide.
Nature Communications · 2025
Dante's team was credited in the Acknowledgements of a 2025 Nature Communications paper — the first near-complete diploid reference genome of the RPE-1 cell line. The research advances the precision of haplotype-resolved genomics, the same field underlying Dante's whole genome sequencing methodology.
Read the publicationAmerican Society of Human Genetics · 2022
Dante has presented clinical genomics work at the American Society of Human Genetics annual meeting — the principal scientific forum for human genetics research. Presentations are peer-vetted and reviewed by the academic and clinical genetics community alongside work from leading institutional research programs worldwide.
Inbound from hospital genetics teams
Clinical teams and hospital genetics laboratories contact Dante directly to submit patient samples for sequencing and analysis. Physicians initiating that contact independently is itself a measure of clinical confidence.
Findings your physician can act on.
Classified to standards set by the American College of Medical Genetics and Genomics and the Association for Molecular Pathology.
30X Clinical Sequencing
Your entire genome sequenced at 30X coverage — the standard required for clinical-grade diagnosis. Every one of your 6.4 billion letters, read.
200+ Physician-Ready Reports
Comprehensive reporting across cardiology, oncology, rare disease, neurological conditions, and pharmacogenomics — designed to share directly with your specialist, and continually updated for life as science advances.
Secure Genome Manager
A HIPAA and GDPR-compliant portal with lifelong access to your complete clinical insights, new report releases as science advances, and specialist referral guidance.
Full Data Ownership & Privacy
Unrestricted access to your BAM, VCF, and FASTQ files. Your genetic data belongs to you — export it to any independent specialist, at any time, forever.
Dante's secure data architecture was built across multiple, independent GDPR and HIPAA-compliant data protection layers. Your data is never shared with insurers, pharmaceutical companies, or research programs without your explicit consent. You can request deletion at any time.
Full data and privacy policyOne test.
A lifetime of answers.
One kit, sent to your home. Your entire genome sequenced at the clinical standard used for diagnostic decisions. 200+ physician-ready reports delivered to your Genome Manager in 6–8 weeks — permanent and updated as science advances.
Ships within 48 hours · Results in 6–8 weeks
