Rare Disease Health Package
A comprehensive solution for people facing rare and undiagnosed diseases
Whole Genome Sequencing Test is a test for everyone. For people facing rare or undiagnosed diseases, still more!
We solve complex genetic cases by combining phenotypic data and genomic data.
Rare Disease Health Package is a powerful tool that can revolutionize the diagnostic process for rare disease patients.
Dante Labs' goal is to provide answers and closure for rare disease patients and their families.
The Diagnostic Odyssey can be a long and difficult journey, often leaving patients and their families feeling frustrated, isolated, and anxious. Rare Disease Health Package can provide a definitive diagnosis, bringing closure to the diagnostic process and allowing patients and their families to move forward with a better understanding of their condition.
In addition, its ability to provide a comprehensive view of a patient’s genome, save time and money, identify potential treatments and management strategies, identify genetic risk factors for other conditions, and provide answers and closure for patients and their families makes it an invaluable tool in the fight against rare diseases.
You are not alone! Dante Labs provides a Pre- and Post- Telemedicine Consultation with a Specialist Doctor For Free.
Pre-Telemedicine Consultations
Pre-telemedicine consultations can help you prepare for getting tested. Rare disease patients often have complex medical histories, and it can be challenging for them to communicate all of their symptoms and concerns during a short consultation. Pre-telemedicine consultations lets you provide a comprehensive overview about your health status. This leads to more efficient and effective consultations, as the specialist will have a better understanding of your medical history and concerns.
Post-Telemedicine Consultations
Post-telemedicine consultations can help you get the diagnosis and, finally, end your Diagostic Odyssey. Moreove you can stay on track with your treatment plan, as you can check in with their specialist regularly and make adjustments to your treatment plan if necessary.
Get access to specialists
Get access to specialists who may not be available in your area. Many rare diseases are so rare that there are only a few specialists who have experience diagnosing and treating them. This can make it challenging for patients to find a specialist who is knowledgeable about their condition and can provide them with the care they need. Dante Labs helps you bridge this gap allowing you to connect with specialists from anywhere in the world.
Your Privacy and Security is essential to us.
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Rare Disease Health Package involves the collection and storage of sensitive personal information, and protecting the privacy and security of this data is of paramount importance for us.
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You have the right to control your genetic information, and Dante Labs' commitment to not selling genomic and personal information ensures that you maintain control over your data.
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Dante Labs' sequencing of all tests in the EU and USA and compliance with GDPR and HIPAA regulations ensures that MyRare data is protected according to rigorous legal and ethical standards.
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By not sending samples to China, Dante Labs is taking proactive steps to protect individuals' genomic and personal information from unauthorized access and use, providing peace of mind to those undergoing the test.
Rare Disease Health Package: 30X Coverage Clinical-Grade Whole Genome Sequencing.
Clinical-grade WGS
When conducting Whole Genome Sequencing, one critical factor to consider is the depth of coverage or the number of times each base pair is read during sequencing. In clinical-grade WGS, a coverage depth of 30X is considered the gold standard.
30X Coverage
The 30X coverage means that each base pair has been sequenced 30 times, ensuring high accuracy and confidence in the results. The depth of coverage is critical because sequencing errors can occur due to technical limitations, such as DNA damage or sequencing noise. The likelihood of detecting these errors decreases with increased coverage depth, and a 30X depth of coverage has been shown to achieve a high level of accuracy in identifying variants.
Identifying Variants
Achieving 30X coverage is particularly crucial for identifying variants that may be causative of rare diseases or other conditions. Such variants are often rare and may only be present in a small fraction of the genome. A 30X depth of coverage ensures that these rare variants are detected with high confidence, increasing the chances of accurate diagnosis and treatment.
Accurate sequencing
A 30X depth of coverage is also essential for identifying structural variants, such as insertions, deletions, and inversions. These structural variants can be challenging to detect, and low coverage depths may result in inaccurate or missed calls. By contrast, a 30X depth of coverage provides sufficient sequencing data to accurately detect these structural variants. Achieving a 30X depth of coverage in clinical-grade WGS is of paramount importance. The accuracy and reliability of WGS results depend on the depth of coverage, particularly for identifying rare variants and structural variants that may be causative of rare diseases or other conditions. A 30X depth of coverage ensures high confidence in results and is necessary for reliable population genetics studies. While achieving 30X coverage is not without challenges, the benefits of accurate and reliable WGS results make it a critical consideration in clinical-grade WGS.
Fill Out the form to get a personalized report based on the analysis of your genetic data.
Sammy Basso experiences the Rare Disease Health Package from Dante Labs
Sammy Basso, biologist, researcher and patient with the rare disease Progeria decided to try our Rare Disease Health Package to discover 100% of his DNA by supporting our project to help rare disease patients like him or people without a diagnosis to find a correct diagnosis, learn more about the disease, receive treatment and a personalized care strategy.
