Inflammation is a complex phenomenon that the body puts in place to defend itself from the attack of pathogens or other potentially harmful factors. However, when inflammation is unleashed without an apparent cause, causing tissue damage, it becomes a pathological phenomenon. Also in this case genetic predisposition plays important roles in making a subject predisposed to the development of this type of condition. At the basis of autoinflammatory diseases there may be gene mutations that increase the secretion of molecules (such as cytokines) with a pro-inflammatory action. Affected individuals often experience fever and other tissue-specific phenomena.
This panel is particularly suitable for subjects with signs and symptoms of autoinflammatory phenomena or for those who, due to familiarity, have an increased risk of incurring conditions of this type.
The analysis takes into consideration the mutation of germline DNA, it investigates SNP and Indel mutations up to 150 bp.
- Available in less than 24 hours
- Based on Whole Genome Sequencing
- More than 13 genes analyzed
- Investigates SNP and Indel mutations up to 150 bp
List of main conditions:
- Familial Mediterranean Fever
- Familial Cold Autoinflammatory Syndrome
- Blau syndrome
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Using a simple at home blood sample, we can collect the 100% of your DNA and analyze the genetic sequence in our lab.
The sequence is divided into several parts, amplified, grouped in clusters and then sequenced.
This sequencing process reveals the order of nucleotides that make up the original DNA sample.
We then compare the genome with a generic and globally recognized reference DNA sequence.
Simple Blood Sample Collection
Painless, quick at home sample collection. User friendly device with CE-IVD mark and FDA approval.
Simply follow the packaging instructions and send the sample back using the pre-paid returns label.
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Our extensive network of geneticists will provide you with specialized genetic counseling on the topics that are most relevant for you such as diet and nutrition, fitness, injuries and many more.
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