Neurofibromatosis is a hereditary condition characterized by the onset of benign tumors, called neurofibromas, along the course of the nerves. The two main types differ clinically and genetically, although they belong to the same nosological entity. The genetic alterations underlying Neurofibromatosis compromise the tumor suppressor function of the genes involved, thus opening the way to uncontrolled cell proliferation.
This panel supports the diagnosis of Neurofibromatosis, which generally occurs in adulthood, but is also useful for those who have a positive family history for the pathology (this is the main risk factor).
The analysis takes into consideration the mutation of germline DNA, it investigates SNP and Indel mutations up to 150 bp.
- Available in less than 24 hours
- Based on Whole Genome Sequencing
- 5 genes analyzed
- Investigates SNP and Indel mutations up to 150 bp
List of main conditions:
- Neurofibromatosis type 1/2
This product is only meant for customers who already purchased a Dante Genome Test