Skeletal and Connective Tissue Disorders Panel

This product is only meant for customers who already purchased a Dante Genome Test

The genetic variants analyzed in this panel are closely related to or potentially the cause of scheletal or connective tissue conditions
Skeletal and connective tissue disorders panel is a comprehensive panel that tests for genetic variants associated with a wide range of skeletal and connective tissue disorders, including osteogenesis imperfecta, Ehlers-Danlos syndrome, and Marfan syndrome. These disorders are caused by mutations in genes involved in the development and function of bone, cartilage, and connective tissue, and this panel tests for genetic variants that are known to affect these processes.
This panel is designed for individuals with a family history of skeletal and connective tissue disorders or individuals with symptoms of these conditions, such as bone fragility, joint hypermobility, and scoliosis. Genetic testing can confirm a diagnosis, provide information on disease severity and progression, and inform treatment and management decisions. Testing can also inform family planning decisions and provide reassurance for unaffected family members.

The analysis takes into consideration the mutation of germline DNA, it investigates SNP and Indel mutations up to 150 bp.

  • Available in less than 24 hours
  • Based on Whole Genome Sequencing
  • More than 415 genes analyzed
  • Investigates SNP and Indel mutations up to 150 bp

List of main conditions:
  • Skeletal Dysplasia
  • Osteogenesis Imperfecta
  • Achondroplasia
  • Achondrogenesis
  • Loeys-Dietz Syndrome

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