This product is only meant for customers who already purchased a Dante Genome Test

CADASIL is an acronym for Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy, a rare and complex neurological condition characterized by occlusion of cerebral arterioles, leading to stroke and disability. The pathology, in 90% of cases, is caused by mutations in the NOTCH3 gene, while the remaining cases are attributable to HTRA1.
This panel is indicated for subjects with a family history of the disease and/or for those who show signs and symptoms attributable to it, such as recurrent ischemic episodes and migraines, dementia and psychiatric manifestations.

The analysis takes into consideration the mutation of germline DNA, it investigates SNP and Indel mutations up to 150 bp.
  • Available in less than 24 hours
  • Based on Whole Genome Sequencing
  • 2 genes analyzed
  • Investigates SNP and Indel mutations up to 150 bp

List of main conditions:
  • Cerebral arteriopathy with subcortical infarcts and leukoencephalopathy
  • CARASIL syndrome

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